College Football Week 11 Odds and Preview: USC at Indiana, Texas at LSU
College football Week 11 odds, as of Tuesday morning, November 10, 2026, 9:15 AM ET: Indiana is a 7.5-point favorite over USC, LSU is favored by 3.5 to 4.5 over Texas, and Georgia is a 15.5-point favorite over Missouri. Those three games, plus Michigan at Oregon, headline Saturday, November 14.
The biggest move is Oregon, which opened at -5.5 against Michigan and is now -10.5 to -11.5, with the total down from 44.5 to 38. Lines are now posted on all 25 games, including Oklahoma State as a 3.5-point favorite over Texas Tech.
The second CFP rankings come out Tuesday night. This page carries no pick: it covers lines, line moves and player status.
College football Week 11 odds for every game
The table is our own snapshot of SportsbookReview's college football board as of Tuesday morning, November 10, 2026, 9:15 AM ET, across BetMGM, bet365, DraftKings, FanDuel, Fanatics, BetRivers and Caesars. The spread and total are the range across the books that had the game posted. The moneyline is DraftKings unless the row says BetMGM.
Kickoff times and networks are from FBSchedules' Week 11 television selections. Five Big 12 and SEC games were six-day selections, and their kickoff times were still pending on Tuesday morning. Rankings are the CFP committee's first set from November 3, which comes out again on Tuesday. Where each team would land now is on our bowl projections 2026-27 page.
| Kickoff (ET) | Game | Spread | Total | Moneyline |
|---|---|---|---|---|
| Thu. 8:00 PM, ESPN | Memphis at USF | Memphis -3.5 to -4.5 | 49.5 to 50.5 | Memphis -192 / USF +160 |
| Fri. 7:00 PM, ESPN | Florida State at Pittsburgh | Pitt -3.5 | 53.5 to 54.5 | FSU +142 / Pitt -170 |
| Fri. 9:00 PM, FOX | Illinois at No. 8 UCLA | UCLA -9.5 to -10.5 | 47.5 to 48 | Illinois +300 / UCLA -380 |
| Fri. 10:15 PM, ESPN | No. 17 Houston at Colorado | Houston -10.5 to -11.5 | 50.5 to 51.5 | Houston -395 / Colorado +310 |
| Sat. 12:00 PM, ABC | Duke at No. 1 Miami | Miami -12.5 to -13.5 | 53.5 to 54.5 | Duke +410 / Miami -550 |
| Sat. 12:00 PM, ESPN | No. 16 Wake Forest at SMU | Wake -1.5 to SMU -1.5 | 61 to 61.5 | Wake -115 / SMU -105 |
| Sat. 12:00 PM, FOX | Northwestern at No. 12 Ohio State | Ohio State -12.5 | 46.5 | NW +360 / OSU -470 |
| Sat. 12:00 PM, FS1 | Wisconsin at Maryland | Wisconsin -7.5 to -8.5 | 43 to 43.5 | Wisc. -325 / Md. +260 |
| Sat. 12:00 PM, ESPN2 | Auburn at Mississippi State | Auburn -2.5 | 49.5 to 50.5 | Auburn -148 / MSU +124 |
| Sat. 12:45 PM, SECN | No. 5 Alabama at Vanderbilt | Alabama -15.5 to -16.5 | 50.5 | Alabama -850 / Vandy +575 |
| Sat. TBA | Baylor at No. 9 BYU | BYU -7.5 | 48.5 to 49.5 | Baylor +240 / BYU -298 |
| Sat. TBA | No. 3 Utah at No. 22 Arizona | Utah -2.5 | 54.5 to 55 | Utah -142 / Arizona +120 |
| Sat. TBA | No. 15 Texas Tech at Oklahoma State | Oklahoma State -3.5 | 72.5 to 73.5 | TTU +142 / OSU -170 |
| Sat. 3:00 or 3:30 PM, ESPN | No. 13 Tennessee at Texas A&M | Tennessee -2.5 | 42.5 to 43.5 | Tenn. -135 / A&M +114 |
| Sat. 3:30 PM, CBS | No. 20 USC at No. 4 Indiana | Indiana -7.5 | 49.5 to 50.5 | USC +230 / Indiana -285 |
| Sat. 3:30 PM, ABC | No. 18 Missouri at No. 2 Georgia | Georgia -15.5 | 47 to 47.5 | Missouri +500 / Georgia -700 |
| Sat. 3:30 PM, NBC | Boston College at No. 11 Notre Dame | Notre Dame -28.5 to -30.5 | 51.5 to 52.5 | BC +1800 / ND -5000 |
| Sat. 3:30 PM, FS1 | Michigan at No. 23 Oregon | Oregon -10.5 to -11.5 | 37.5 to 38.5 | Michigan +340 / Oregon -440 |
| Sat. 4:15 PM, SECN | No. 10 Ole Miss at Oklahoma | Ole Miss -1 to -1.5 | 48.5 to 49.5 | Ole Miss -115 / Oklahoma -105 |
| Sat. 6:00 PM, USA | Oregon State at No. 25 Boise State | Boise State -12.5 to -13.5 | 65.5 to 66 | Ore. St. +390 / Boise -520 |
| Sat. 6:15 or 7:00 PM, ESPN | No. 24 Florida at No. 6 Kentucky | Kentucky -3.5 | 52.5 to 53.5 | Florida +145 / Kentucky -175 |
| Sat. 7:00 PM, FS1 | Minnesota at Penn State | Penn State -8.5 to -9.5 | 41.5 to 42.5 | Minn. +270 / PSU -340 |
| Sat. 7:30 PM, NBC | Purdue at No. 19 Iowa | Iowa -16.5 to -17.5 | 47.5 | Purdue +625 / Iowa -950 |
| Sat. 7:30 PM, ABC | No. 7 Texas at No. 14 LSU | LSU -3.5 to -4.5 | 45.5 to 46.5 | Texas +150 / LSU -180 |
| Sat. 7:45 PM, SECN | No. 21 South Carolina at Arkansas | South Carolina -7.5 | 51.5 | S. Carolina -310 / Ark. +250 |
We cross-checked every favorite against VegasInsider's consensus board on Tuesday morning. Shop the key numbers: Wake Forest and SMU flip between -1.5 and +1.5 by book, and Wisconsin is 7.5 or 8.5. Our free plays for the week are posted on the free picks page.
Biggest early line moves for Week 11
"Opened" is SportsbookReview's opening number, which for most of these games is the lookahead line posted before Saturday's results. The table shows where the line sits now and how the total moved with it.
| Game | Opened | Now | Total |
|---|---|---|---|
| Michigan at Oregon | Oregon -5.5 | Oregon -10.5 to -11.5 | 44.5 to 38 |
| Oregon State at Boise State | Boise State -4.5 | Boise State -12.5 to -13.5 | 62.5 to 65.5 |
| Alabama at Vanderbilt | Alabama -19.5 | Alabama -15.5 to -16.5 | 54.5 to 50.5 |
| Memphis at USF | Memphis -6.5 | Memphis -3.5 to -4.5 | 49.5 to 50.5 now |
| Wake Forest at SMU | Wake Forest -2 | Wake -1.5 to SMU -1.5 | 61 to 61.5 now |
| Wisconsin at Maryland | Wisconsin -9.5 | Wisconsin -7.5 to -8.5 | 42.5 to 43.5 |
| Texas at LSU | LSU -4.5 | LSU -3.5 to -4.5 | 46.5 to 46 |
Oregon's move is the week's story: a 5.5-point lookahead line is now 10.5 to 11.5 after Oregon beat Ohio State 41-28 and Michigan lost 15-6 to Michigan State, and the total fell from 44.5 to 38. Boise State went from -4.5 to -12.5 to -13.5 over Oregon State after Texas State beat Oregon State 42-21.
Oklahoma State is a 3.5-point favorite over Texas Tech at every book, a number we could not tie to confirmed injury news by Tuesday morning, so check both quarterbacks before Saturday. Memphis has dropped from 6.5 to 3.5 to 4.5 at USF.
USC vs Indiana odds and preview
Both teams had a bye on November 7. USC is 7-2 and beat Ohio State 30-18 on October 31; Indiana is 8-1 and beat Minnesota 23-16 in overtime the same day.
Indiana's quarterback is the open question: Josh Hoover hurt his right shoulder against Ohio State and was pulled against Minnesota, and Curt Cignetti again declined on November 9 to say whether he or Grant Wilson starts.
Kalshi gives Indiana a 43 to 45% chance to win the Big Ten and USC 2 to 4%, so the market treats this as Indiana's race to lose. The spread is 7.5 at every book, a half-point past the key number 7. Indiana's title price is in our national championship odds.
Texas vs LSU odds and preview
Texas is 7-2 after a 34-20 win at Missouri in which Arch Manning threw for 297 yards and three touchdowns, per the CBS Sports box score. LSU is 6-3 after losing 31-13 to Alabama at home; Sam Leavitt threw for 380 yards without a touchdown.
LSU is still favored at home, now by 3.5 to 4.5 after opening at 4.5.
The market has LSU at 62% with the vig removed, the smallest edge for a home favorite among the ranked games on this board. Kalshi has Texas at 71 to 74 cents to make the playoff and LSU at 25 to 26, so the loser is in real trouble. Our CFP predictions have Texas as the 8 seed.
Missouri vs Georgia odds and preview
Georgia is 8-1 after beating Ole Miss 42-7, with Gunner Stockton accounting for five touchdowns, per the CBS Sports box score. Missouri is 6-3 after a 34-20 loss to Texas, and quarterback Austin Simmons left that game in the fourth quarter with a leg injury. Missouri has not released a diagnosis, so his status is unresolved.
Georgia is the national title favorite at about 28.6% on Kalshi and Polymarket, and Kalshi gives the Bulldogs a 54 to 56% chance to win the SEC. A 15.5-point spread against a ranked SEC team shows how far the market has moved toward Georgia since its title price opened at +1000.
Michigan vs Oregon odds and preview
Oregon is a 10.5 to 11.5 point favorite over Michigan on Saturday at 3:30 PM ET on FS1, with the total at 37.5 to 38.5 and DraftKings at Michigan +340 and Oregon -440, about 22% to 78% with the vig removed. The implied score is Oregon 24.5, Michigan 13.5.
Oregon is 6-3 after beating Ohio State 41-28 with Dylan Raiola at quarterback and Dante Moore out for the season. Michigan is 5-4 after losing 15-6 at Michigan State; Tommy Carr threw two interceptions and has started since Bryce Underwood was benched on October 17. The line opened at Oregon -5.5, and the total fell from 44.5 to 38.
Key injuries and player status for Week 11
Statuses below are the most recent we could confirm from two or more sources; the Indiana and Missouri quarterback rows were rechecked on Tuesday, November 10. Several are unresolved after Saturday's games, and they can change before kickoff: the SEC and ACC publish availability reports midweek, and the Big Ten publishes two hours before kickoff. We recheck this table midweek.
| Player | Team | Pos. | Status | Source, date |
|---|---|---|---|---|
| Josh Hoover | Indiana | QB | Unresolved. Shoulder injury; pulled vs Minnesota. Cignetti declined to name a starter on Nov. 9 | IPM, ESPN, Fox Sports, Nov. 9 |
| Austin Simmons | Missouri | QB | Unresolved. Left the Texas game with a leg injury, returned, and said he was fine physically; no update since | Yahoo; The Maneater, Nov. 7 |
| Keelon Russell | Alabama | QB | Hurt his left ankle at LSU, returned and finished; called it "not a big injury"; no designation yet | AP; Heavy, Nov. 7 |
| Sam Leavitt | LSU | QB | Played the full game vs Alabama; SI noted a lingering lower-body injury | CBS box; SI, Nov. 7 |
| Colin Simmons | Texas | EDGE | Questionable (high ankle) entering the Missouri game; recheck midweek | SI report, Nov. 5 |
| Ellis Robinson IV, Craig Dandridge Jr. | Georgia | CB, WR | Both left the Ole Miss game; statuses for Missouri not yet given | DawgNation, Nov. 7 to 8 |
| Jordon Davison | Oregon | RB | Out vs Ohio State (lower extremity); recheck midweek | SI, Nov. 7 |
| Dante Moore | Oregon | QB | Out for the season (concussion); Dylan Raiola starts | KATU; SI, Nov. 7 |
| Julian Sayin | Ohio State | QB | Out; Ryan Day said Nov. 5 the staff is planning for him to miss the regular season | Local 12, Nov. 5 |
| Malachi Toney | Miami | WR | Out 4 to 6 weeks after ankle surgery | AP, Nov. 4 |
| Kewan Lacy | Ole Miss | RB | Out (left shoulder) vs Georgia; recheck midweek | SI report, Nov. 5 |
| Nico Iamaleava | UCLA | QB | Out for the season (torn ACL) | SI report, Nov. 5 |
The two quarterback situations that matter most for the lines are Indiana's and Missouri's. If Indiana names Grant Wilson, the USC spread should shrink; if Missouri is without Austin Simmons, the Georgia spread should grow. Keelon Russell finishing the LSU game has not stopped the Alabama line from falling from 19.5 to 15.5 to 16.5.
Other Week 11 college football games
The highest totals of the week are in the Group of Six: North Texas at UTSA is 76.5 to 77 and Florida Atlantic at Tulsa is 73.5 to 74.5. Memphis at USF opens the week on Thursday night, and Florida State plays its first game since firing Mike Norvell at Pittsburgh on Friday as a 3.5-point underdog.
Among the other Power 4 games, Clemson is a 12.5 to 13.5 point favorite over Georgia Tech, Virginia is -9.5 to -10.5 against California and Nebraska is -13.5 at Rutgers.
Syracuse is -2.5 to -3 at North Carolina State, Louisville is -3.5 at North Carolina and Virginia Tech is -15.5 against Stanford.
The Heisman race runs through this slate too: CJ Carr, Jeremiah Smith, Devon Dampier, Gunner Stockton and Sam Leavitt all play Saturday. Our Heisman odds page has the board after Week 10.
Full game pages: USC vs Indiana, Texas vs LSU, Missouri vs Georgia and Michigan vs Oregon.