College Football Week 6 Odds and Preview: Georgia at Alabama Leads the Board
The college football Week 6 odds have moved more this week than any board this season. No. 2 Georgia opened as the favorite at No. 6 Alabama and is now a 1.5-point underdog, with Hurricane Isaias knocking five points off that total. No. 19 USC opened as a road favorite at Penn State and is now getting 1.5. And Oregon will play UCLA without quarterback Dante Moore. Here is every ranked line as of Friday, October 9, 2026, about 2:30 AM ET, what moved and the injuries that matter for Saturday, October 10.
College football Week 6 odds for ranked games
Here is the board for the Week 6 games with ranked teams. Rankings are the AP poll released October 4. The spread and total columns give the range across BetMGM, bet365, DraftKings, FanDuel, Fanatics, BetRivers and Caesars on SportsbookReview's board, and the moneyline is DraftKings unless noted. Kickoff times are Eastern.
| Kickoff (ET) | Game | Spread | Total | Moneyline |
|---|---|---|---|---|
| Sat 12:00 | No. 7 Indiana at Nebraska | Indiana -7.5 | 47.5 to 48.5 | IND -305 / NEB +245 |
| Sat 12:00 | Texas A&M at No. 14 Missouri | Missouri -3.5 | 48.5 | MIZ -175 / TAMU +145 |
| Sat 12:45 | South Carolina at No. 16 Florida | Florida -11.5 to -12.5 | 59.5 to 60 | FLA -470 / SC +360 |
| Sat 3:30 | No. 1 Texas vs Oklahoma (Dallas) | Texas -7.5 | 39 to 40 | TEX -330 / OU +260 (FanDuel) |
| Sat 3:30 | No. 21 UCLA at No. 13 Oregon | Oregon -11.5 to -12.5 | 58.5 to 59.5 | ORE -455 / UCLA +350 |
| Sat 7:00 | No. 10 LSU at Kentucky | LSU -8.5 to -9.5 | 51.5 to 52.5 | LSU -345 / UK +275 |
| Sat 7:30 | No. 2 Georgia at No. 6 Alabama | Alabama -1.5 to -2.5 | 51 to 51.5 | ALA -122 / UGA +102 |
| Sat 7:30 | No. 19 USC at Penn State | Penn State -1.5 | 54.5 to 55 | PSU -122 / USC +102 |
Sources: SportsbookReview's odds board for the opener and each book's current number, checked against VegasInsider's Week 6 board and the line reports in our game pages. DraftKings' Red River moneyline (-218) and total (48.5) have been out of line with every other book all week, so FanDuel's moneyline is shown for that game.
Biggest Week 6 line moves
Opened is the opening number on SportsbookReview's board; now is the number most books show Friday morning.
| Game | Opened | Now | Move |
|---|---|---|---|
| Georgia at Alabama | Georgia -1.5, total 56.5 | Alabama -1.5, total 51.5 | 3 points to Alabama; total down 5 |
| USC at Penn State | USC -2 | Penn State -1.5 | 3.5 points to Penn State |
| South Carolina at Florida | Florida -14 | Florida -11.5 | 2.5 points to South Carolina |
| Indiana at Nebraska | Indiana -9.5, total 51.5 | Indiana -7.5, total 48 | 2 points to Nebraska; total down 3.5 |
| UCLA at Oregon | Oregon -13 | Oregon -11.5 | 1.5 points to UCLA |
| LSU at Kentucky | LSU -10, total 55.5 | LSU -8.5, total 52 | 1.5 points to Kentucky |
| Oklahoma vs Texas | Texas -6.5 | Texas -7.5 | 1 point to Texas |
Two of the eight ranked games have flipped favorites since the lines opened, which is unusual for a single week. The Georgia at Alabama total is the number I would watch most closely, because it is tied to a forecast that has already changed twice. If you want to know why a half point around 3 or 7 matters so much, the betting basics hub walks through key numbers, and the live odds page is where to watch the board move into Saturday.
Georgia at Alabama odds and the hurricane forecast
Georgia at Alabama is the game of the week, and the market now leans Alabama: with the margin removed, the DraftKings moneylines make Alabama a 52.6% favorite. As of Thursday, October 8, the game is still scheduled for 7:30 PM ET, and ABC 33/40 meteorologist James Spann expects the worst of Hurricane Isaias Saturday morning into early afternoon, with most of the rain north of Tuscaloosa by kickoff. The full breakdown, with odds at seven books and the series history, is in our Georgia vs Alabama prediction.
Texas vs Oklahoma odds for the Red River game
The number that jumps out in Texas vs Oklahoma is still the total. At 39 to 40 it is about nine points lower than any other ranked game this week, which tells you the market expects Oklahoma's offense to keep struggling against the Texas defense. The spread has settled at Texas -7.5 at every book, and with the margin removed, FanDuel's moneylines make Texas a 73.4% favorite. Our Texas vs Oklahoma prediction has the full board.
UCLA at Oregon odds without Dante Moore
Oregon listed quarterback Dante Moore as out with a concussion on its first availability report for the UCLA game, and Dylan Raiola, the Nebraska transfer who finished the 41-27 win at USC, is set to start. The spread barely reacted: it had already slid from Oregon -13 to -11.5 earlier in the week while Moore's status was unclear. UCLA comes in unbeaten. More in our UCLA vs Oregon prediction.
LSU at Kentucky odds and preview
LSU at Kentucky has drifted toward the underdog all week: LSU opened -10 on SportsbookReview's board and is -8.5 at six of seven books, and the total has come down from 55.5 to 51.5 to 52.5. Kentucky won at South Carolina on a two-point conversion in overtime after trailing by 17. With the margin removed, DraftKings' moneylines make LSU a 74.4% favorite. See our LSU vs Kentucky prediction for the rest.
Key Week 6 injuries and player status
These come from the first availability reports released Wednesday, October 7, each confirmed by at least two outlets. Conferences update the reports Thursday and Friday nights and again about two hours before kickoff, so treat anything listed as questionable as unresolved.
| Player | Team | Pos | Status | As of |
|---|---|---|---|---|
| Dante Moore | Oregon | QB | Out (concussion); Dylan Raiola starts | Oct 7 |
| Chauncey Bowens | Georgia | RB | Out | Oct 7 |
| Nate Frazier | Georgia | RB | Off the injury report | Oct 7 |
| Isiah Canion | Georgia | WR | Questionable (leg) | Oct 7 |
| Josh Ford | Alabama | TE | Questionable | Oct 7 |
| Justin Hill, Desmond Umeozulu | Alabama | LB | Out | Oct 7 |
Other Week 6 games worth a look
Penn State is now a 1.5-point favorite over USC for the White Out after USC opened as a 2-point road favorite; our USC vs Penn State prediction has the details. No. 7 Indiana is -7.5 at Nebraska, but the total there has dropped from 51.5 to about 48 (see our Indiana vs Nebraska prediction). No. 16 Florida has come down from -14 to -11.5 against South Carolina after the 45-17 loss at Missouri, and No. 14 Missouri is -3.5 against Texas A&M. On Friday night, Iowa State is about a 10.5-point underdog at No. 8 BYU.
Last week's board, with every closing line, is on our college football Week 5 preview.
Week 6 college football odds questions
Who is favored in Georgia vs Alabama in 2026?+
What is the spread for Texas vs Oklahoma in 2026?+
Is Dante Moore playing against UCLA?+
Will Hurricane Isaias affect college football Week 6?+
What were the biggest college football Week 6 line moves?+
Next up: Week 6 is in the books. See the college football Week 7 preview for the October 17 lines, led by Ohio State at Indiana, and our CFP predictions for the playoff picture.