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NFL Week 7 Odds and Predictions 2026: Lines, Moves, Injuries

NFL Week 7 Odds and Predictions 2026: Lines, Moves, Injuries

This week's odds: NFL Week 10 odds, line moves and injuries for all 14 games.

NFL Week 7 opens Thursday night in Chicago, where the Bears are 2.5 to 3-point favorites over the New England Patriots, as of Thursday afternoon, October 22, 2026.

The biggest story on the board is Monday night in Philadelphia: Jalen Hurts is out for the season with blood clots in his lungs, and the Dallas Cowboys are 4 to 4.5-point road favorites over an Eagles team that led on the lookahead line. The Houston Texans are the biggest favorite at 10.5 over the Giants.

The Week 7 board in brief
Fourteen games, four byes (Bills, Jaguars, Chargers, Commanders) and an international game, Steelers vs. Saints at the Stade de France in Paris at 9:30 AM ET Sunday, where Pittsburgh has moved through the 3 to -3.5. Injuries drive the week: Hurts is done for 2026, the Rams lost Davante Adams for 6 to 10 weeks and fell from 6 to 4.5 at Las Vegas, Lamar Jackson was limited Wednesday and Thursday ahead of Baltimore's division game with Cincinnati, and Baker Mayfield (thumb) practiced in full both days for Tampa Bay but has not been named the starter. San Francisco finished Week 6 at 6-0 with a 23-17 win over Washington but lost Mike Evans in the game, and the 49ers dipped from 4.5 to 2.5 to 3 at Atlanta.
HOU -10.5
Biggest favorite
vs Giants, 42.5 to 43.5 total
DAL -4.5
Biggest swing
Eagles were -3 on the lookahead
53.5
Highest total
Packers at Lions
PIT -3.5
Through the 3
Opened 1.5 in Paris

NFL Week 7 odds for every game

Spread and total across seven books on Action Network's odds board, Thursday, October 22, 2026, 5:45 PM ET. Moneyline from FanDuel (away / home). Checked against ScoresAndOdds
KickoffGameSpreadTotalFD ML
Thu 8:15 PMPatriots at BearsCHI -2.5 to -350.5 to 51+134 / -158
Sun 9:30 AMSteelers at SaintsPIT -3 to -3.544 to 44.5-174 / +144
Sun 1:00 PMColts at VikingsMIN -6.541.5+240 / -295
Sun 1:00 PMDolphins at JetsNYJ -4.5 to -539 to 39.5+194 / -235
Sun 1:00 PMBengals at RavensBAL -1 to -1.548.5 to 49+102 / -120
Sun 1:00 PMBrowns at TitansCLE -1.5 to -2.537.5-126 / +108
Sun 1:00 PMBuccaneers at PanthersCAR -2.5 to -344 to 44.5+130 / -154
Sun 1:00 PM49ers at FalconsSF -2.5 to -349.5 to 50-148 / +126
Sun 1:00 PMGiants at TexansHOU -10.542.5 to 43.5+410 / -550
Sun 4:05 PMBroncos at CardinalsDEN -4 to -4.543 to 43.5-210 / +176
Sun 4:25 PMRams at RaidersLAR -3.5 to -4.548.5-215 / +180
Sun 4:25 PMPackers at LionsDET -3 to -3.552.5 to 53.5+144 / -172
Sun 8:20 PMChiefs at SeahawksSEA -2.5 to -342.5+122 / -144
Mon 8:15 PMCowboys at EaglesDAL -4 to -4.544 to 44.5-196 / +164

Thursday's numbers come from Action Network's seven-book board, checked against ScoresAndOdds (SportsbookReview's Week 7 board had not updated since Tuesday). Shop the number: Bears, Panthers, Lions and Seahawks all straddle 3, the most important key number in football. Our guide to key numbers explains why, and you can compare books on our sportsbooks page.

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Biggest NFL Week 7 line moves

Opening line versus the consensus now
GameOpenedNowMove
Cowboys at EaglesEagles -3 (lookahead); Cowboys -6 (reopen)Cowboys -4 to -4.5Flipped after Hurts was lost
Bengals at RavensRavens -3Ravens -1 to -1.5Toward Cincinnati with Jackson still limited
Steelers at SaintsSteelers -1.5Steelers -3 to -3.5Through the 3 toward Pittsburgh
Rams at RaidersRams -6Rams -3.5 to -4.5Toward Las Vegas
49ers at Falcons49ers -4.549ers -2.5 to -3Toward Atlanta
Giants at TexansTexans -8.5Texans -10.5Toward Houston
Steelers at Saints total41.544 to 44.5Up 2.5 to 3
Browns at Titans total36.537.5Up 1
Packers at Lions total52.552.5 to 53.5Up 0 to 1
Chiefs at Seahawks total43.542.5Down 1

Cowboys at Eagles moved the most. Philadelphia was a 3-point favorite on the lookahead line, per CBS Sports. After the Eagles lost 25-14 at home to Carolina without Hurts, the line reopened at Dallas -6, and the market sits at Cowboys -4 to -4.5 after Monday's news that Hurts is out for the season.

Baltimore has gone from 3 to 1 to 1.5 over Cincinnati with Lamar Jackson limited all week. Pittsburgh went from 1.5 to 3 to 3.5 in Paris and the total there climbed from 41.5 to 44 to 44.5.

The Rams came down from 6 to 3.5 to 4.5 after Sean McVay said Adams will miss 6 to 10 weeks, and San Francisco dipped from 4.5 to 2.5 to 3 after failing to cover as a 7.5-point favorite on Monday night.

Patriots vs. Bears: Thursday Night Football

Thu 8:15 PM ETPrime Video
New England Patriots
Away
@
Chicago Bears
Home
Spread
Bears -3
Range -2.5 to -3
Moneyline
+134 / -158
FanDuel, away / home
Total
50.5
Opened 50
New England Patriots 41%Win probability, vig removedChicago Bears 59%
Market-implied score: Bears 26.75, Patriots 23.75.

Both teams are 4-2 and hold wild-card seeds. Chicago won 31-23 at Atlanta with Caleb Williams back from a hamstring injury (30 of 36, 305 yards), and New England beat the Jets 26-19 on three Drake Maye touchdown passes.

The Bears opened 2.5-point favorites and are 3 at six of seven books, with the total up half a point to 50.5. The Patriots are on a short week without wide receiver Romeo Doubs, who went on injured reserve with a shoulder injury.

Every book's number, the final injury report and the implied score are on our Patriots vs Bears prediction page.

Bengals vs. Ravens: does Lamar Jackson return?

Sun 1:00 PM ETCBS
Cincinnati Bengals
Away
@
Baltimore Ravens
Home
Spread
Ravens -1.5
Range -1 to -1.5
Moneyline
+102 / -120
FanDuel, away / home
Total
48.5
Opened 50.5
Cincinnati Bengals 48%Win probability, vig removedBaltimore Ravens 52%
Market-implied score: Ravens 25, Bengals 23.5.

Baltimore is 4-2 but eighth in the AFC after a 13-10 loss at Cleveland, its second straight start for Tyler Huntley in place of Lamar Jackson (ankle). Cincinnati is 3-2 off its bye. The Ravens opened 3-point favorites and are down to 1.5 at most books (1 at BetRivers), with a 48.5 to 49 total.

Jackson was limited Wednesday and Thursday, his first on-field work since the injury. Minter said Jackson wants to play but has to be healthy enough; there is no game status yet.

Packers vs. Lions: the highest total of the week

Sun 4:25 PM ETFOX
Green Bay Packers
Away
@
Detroit Lions
Home
Spread
Lions -3
Range -3 to -3.5
Moneyline
+144 / -172
FanDuel, away / home
Total
53.5
Opened 52.5
Green Bay Packers 39%Win probability, vig removedDetroit Lions 61%
Market-implied score: Lions 28.25, Packers 25.25.

Green Bay has won three straight, the latest 23-13 over Dallas, and holds the NFC No. 5 seed at 4-2. Detroit is 3-2 off its bye and holds the No. 7 seed.

The Lions opened 3-point favorites, went to 3.5, and came back to 3 at five of seven books after Jordan Love was a full participant Thursday; the total has ticked up from 52.5 to 53.5, the highest on the board. Running back Josh Jacobs is eligible for Green Bay after coming off the Commissioner's Exempt List and practiced Thursday.

Cowboys vs. Eagles: Monday Night Football

Mon 8:15 PM ETESPN/ABC
Dallas Cowboys
Away
@
Philadelphia Eagles
Home
Spread
Cowboys -4.5
Range -4 to -4.5
Moneyline
-196 / +164
FanDuel, away / home
Total
44.5
Opened 45
Dallas Cowboys 64%Win probability, vig removedPhiladelphia Eagles 36%
Market-implied score: Cowboys 24.5, Eagles 20.

Both teams are 2-4. Dallas lost 23-13 at Green Bay with Dak Prescott throwing two interceptions, and Philadelphia has lost four straight. The Eagles said Monday that Hurts has blood clots in both lungs and a leg, and multiple outlets report he is expected to miss the rest of the season.

Tanner McKee, who started the Week 6 loss, is the expected starter. Saquon Barkley (hamstring) returned to practice Thursday after missing two games and is in line to play, per NFL Network. Dallas is 4.5 at four books and 4 at three, with a 44 to 44.5 total.

NFL Week 7 key injuries and player status

Status as of Thursday afternoon, October 22, 2026
PlayerTeamPosStatusSource
Jalen HurtsPHIQBOut for the season (blood clots). On injured reserveNFL.com, CBS Sports, ESPN (Oct 19)
Lamar JacksonBALQBAnkle. Limited Wednesday and Thursday. No game status yet. UnresolvedRavens.com, NFL.com, PFT (Oct 22)
Baker MayfieldTBQBThumb. Full practice Wednesday and Thursday; Todd Bowles decides Friday. UnresolvedBuccaneers.com, NFL.com, RotoWire (Oct 22)
Saquon BarkleyPHIRBHamstring. Back at practice Thursday; NFL Network says he is in line to play Monday. UnresolvedNFL.com, NBC Sports Philadelphia, UPI (Oct 22)
Jordan LoveGBQBBack. Limited Wednesday, full participant ThursdayPackers.com, NFL.com, PFT (Oct 22)
Josh SimmonsKCLTBulging disc. Placed on injured reserve Thursday; eligible Week 11Chiefs.com, ESPN, CBS Sports (Oct 22)
Zach CharbonnetSEARBKnee. Activated from PUP Thursday; playing Sunday is possible per Mike MacdonaldNFL.com, Field Level Media, Heavy (Oct 22)
Davante AdamsLARWRRuptured hamstring tendon. On injured reserve; 6 to 10 weeksRams.com, CBS Sports, NBC Sports (Oct 20)
Mike EvansSFWRAchilles. Did not practice Wednesday; Thursday report not posted by 5:45 PM ET. Unresolved49ers.com, CBS Sports, NFL.com (Oct 21)
J.J. McCarthyNYGQBNamed the Week 7 starter Wednesday; Jameis Winston benchedGiants.com, NFL.com, CBS Sports (Oct 21)

Game designations come Friday (Saturday for the Monday game); anything marked unresolved is not a final status. The Giants' Jaxson Dart is out for the season (knee).

Other NFL Week 7 games

In Paris, Pittsburgh (4-2) is a 3 to 3.5-point favorite over New Orleans (2-4) after opening at 1.5. San Francisco (6-0) is 2.5 at Atlanta at most books with a 49.5 to 50 total. Houston lays 10.5 against a Giants team starting J.J. McCarthy. Kansas City (5-0) is a 2.5-point underdog at Seattle on Sunday night, 3 at DraftKings.

The Rams are 3.5 to 4.5-point favorites at Las Vegas without Adams, Denver is 4 to 4.5 at Arizona, Minnesota is 6.5 over Indianapolis coming off its bye, the Jets lay 4.5 to 5 against winless Miami, Carolina is 2.5 to 3 over Tampa Bay, and Cleveland is 1.5 to 2.5 at Tennessee with the lowest total on the board, 37.5.

Looking for a play, not just a line?
This preview is market data only. For actual picks, check our free picks or our premium picks and packages.

Survivor players: see our Week 7 survivor picks.

Full game pages: Patriots vs Bears prediction, Cowboys vs Eagles prediction, Packers vs Lions prediction and Chiefs vs Seahawks prediction.

NFL Week 7 odds questions

Who is the biggest favorite in NFL Week 7 2026?+
The Houston Texans are the biggest favorite in Week 7 at 10.5 points over the New York Giants as of October 22, 2026, with a total of 42.5 to 43.5 and a FanDuel moneyline of -550.
What is the line for Patriots vs. Bears on Thursday Night Football?+
Chicago is a 2.5 to 3-point home favorite over New England as of October 22, 2026, with most books at 3, and the total is 50.5. FanDuel has the Bears -158 and the Patriots +134.
Why are the Cowboys favored over the Eagles?+
Jalen Hurts is expected to miss the rest of the season with blood clots in his lungs, and Philadelphia has lost four straight. The Eagles were 3-point favorites on the lookahead line, and Dallas is a 4 to 4.5-point road favorite as of October 22, 2026.
Is Lamar Jackson playing in Week 7?+
Unresolved as of Thursday, October 22, 2026. Jackson has missed two straight games with an ankle injury, and he was limited in practice Wednesday and Thursday with no game status announced. Baltimore is a 1 to 1.5-point home favorite over Cincinnati.
Which teams are on bye in NFL Week 7?+
The Bills, Jaguars, Chargers and Commanders have the Week 7 bye, leaving 14 games from Thursday, October 22 through Monday, October 26, including Steelers vs. Saints in Paris.
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NFL Week 7 Odds and Lines 2026 | Guaranteed Sport Picks